1 R packages
2 Teaching
3 Stuff
4 Publications
 4.1 Statistical papers
 4.2 Applied papers
 4.3 Unpublished

Patrick Brown

Centre for Global Health Research
St. Michael’s Hospital

Department of Statistical Sciences
University of Toronto

Centre for Global Health Research
St. Michael’s Hospital

1 R packages

Maps and projections in R https://journal.r-project.org/archive/2016-1/brown.pdf
Geostatistical modelling http://www.jstatsoft.org/v63/i12
computes observed and expected counts from case and population data. https://cran.r-project.org/packages=diseasemapping
specify generalised linear mixed models in R, with inference done in WinBUGS. https://cran.r-project.org/package=glmmBUGS

2 Teaching

STA 22101S: Methods of Applied Statistics 2

STA 465: Theory and Methods for Complex Spatial Data

3 Stuff

Google scholar’s
information about me
cbc music streams
Ernest Borgnine

4 Publications

4.1 Statistical papers

Lee, JSW, P Nguyen, PE Brown, J Stafford, and N Saint-Jacques. (2017).
“A local-EM algorithm for spatio-temporal disease mapping with aggregated data”.
Spatial Statistics 21, pp. 75–95.

Brown, PE. “Geostatistics in small-area health applications”. In: Handbook of Spatial Epidemiology. Ed. by AB Lawson, S Banerjee, RP Haining, and MD Ugarte. Chapman & Hall/CRC Handbooks of Modern Statistical Methods. Chapman and Hall/CRC, 2016, pp. 211–224. isbn: 9781482253016. url: https://www.taylorfrancis.com/books/e/9781482253023.

— (2016).
“Maps, Coordinate Reference Systems and Visualising Geographic Data with mapmisc”.
R-journal 8.1, pp. 64–91.

Jiang, H, PE Brown, and SD Walter. (2016).
“Inference on cancer screening exam accuracy using population-level administrative data”.
Statistics in Medicine 35, pp. 130–146.

Brown, PE. (2015).
“Model-based Geostatistics the easy way”.
Journal of Statistical Software 63.

Brown, PE, F Chimard, A Remorov, JS Rosenthal, and X Wang. (2014).
“Statistical Inference and Computational Efficiency for Spatial Infectious-Disease Models with Plantation Data”.
Journal of the Royal Statistical Society, Series C Applied Statistics 63, pp. 467–482.

Jiang, H, PE Brown, H Rue, and S Shimakura. (2014).
“Geostatistical survival models for environmental risk assessment with large retrospective cohorts”.
Journal of the Royal Statistical Society, Series A Statistics in Society 177.3, pp. 679–695.

Brown, PE, P Nguyen, J Stafford, and S Ashta. (2013).
“Local-EM and mismeasured data”.
Statistics and Probability Letters 83, pp. 135–140.

Li, Y, PE Brown, H Rue, and DC Gesink. (2012).
“Log Gaussian Cox Processes and spatially aggregated disease incidence data”.
Statistical Methods in Medical Research 21, pp. 479–507.

Li, Y, PE Brown, H Rue, M al-Maini, and P Fortin. (2012).
“Spatial modelling of Lupus incidence over 40 years with changes in census areas”.
Journal of the Royal Statistical Society, Series C Applied Statistics 61, pp. 99–115.

Nguyen, P, PE Brown, and J Stafford. (2012).
“Mapping Cancer Risk in Southwestern Ontario with Changing Census Boundaries”.
Biometrics 68.

Fan, CPS, J Stafford, and PE Brown. (2011).
“Local Likelihood and the EMS Algorithm”.
Journal of Computational and Graphical Statistics 20.3, pp. 750–766.

Brown, PE and H Jiang. (2010).
“Simulation-based power calculations for large cohort studies”.
Biometrical Journal 52.5, pp. 604–615.

Brown, PE and L Zhou. (2010).
“MCMC for generalized linear mixed models with glmmBUGS”.
R-journal 2.

Henrys, PA and PE Brown. (2009).
“Inference for clustered inhomogeneous spatial point processes”.
Biometrics 65.2, pp. 423–430.

Diggle, PJ, V Gomez-Rubio, PE Brown, AG Chetwynd, and S Lorick. (2007).
“Second-order analysis of inhomogeneous spatial point processes using case-control data.”
Biometrics 63, pp. 550–557.

Brown, PE, PJ Diggle, and R Henderson. (2004).
“A model-based approach to quality control of paper production”.
Applied Stochastic Models in Business and Industry 20, pp. 173–184.

Clough, H and PE Brown. (2004).
“It shouldn’t happen to a statistician”.
Significance 1.3, pp. 118–120.

Brown, PE, PJ Diggle, and R Henderson. (2003).
“A non-Gaussian spatial process model for opacity of flocculated paper”.
Scandinavian Journal of Statistics 30, pp. 355–368.

Brown, PE, PJ Diggle, ME Lord, and PC Young. (2001).
“Space-time calibration of radar rainfall data”.
Journal of the Royal Statistical Society, Series C Applied Statistics 50.2, pp. 221–241.

Brown, PE and P de Jong. (2001).
“Nonparametric smoothing using state space techniques”.
Canadian Journal of Statistics 29.1, pp. 37–50.

Brown, PE, KF Karesen, GO Roberts, and S Tonellato. (2000).
“Blur-generated Non-separable Space-time Models”.
Journal of the Royal Statistical Society, Series B Statistical Methodology 62.4, pp. 847–860.

4.2 Applied papers

Saint-Jacques, N, PE Brown, L Nauta, J Boxall, L Parker, and TJB Dummer. (2018).
“Estimating the risk of bladder and kidney cancer from exposure to low-levels of arsenic in drinking water, Nova Scotia, Canada”.
Environment International 110, pp. 95–104.

Weissman, CR, DM Blumberger, PE Brown, M Isserles, TK Rajji, J Downar, BH Mulsant, PB Fitzgerald, and ZJ Daskalakis. (2018).
“Bilateral Repetitive Transcranial Magnetic Stimulation Decreases Suicidal Ideation in Depression”.
Journal of Clinical Psychiatry 79.

Yoo, EH, PE Brown, and Y Eum. (2018).
“Ambient air quality and spatio-temporal patterns of cardiovascular emergency department visits”.
International Journal of Health Geographics 17.18, pp. 1–16.

Aimone, AM, PE Brown, S Owusu-Agyei, SH Zlotkin, and DC Cole. (2017).
“Impact of iron fortification on the geospatial patterns of malaria and non-malaria infection risk among young children: a secondary spatial analysis of clinical trial data from Ghana”.
BMJ Open 7.5.

Barsalou, J, E Jaeggi, CA Laskin, PE Brown, SY Tian, RM Hamilton, and ED Silverman. (2017).
“Prenatal exposure to antimalarials decreases the risk of cardiac but not non-cardiac neonatal lupus: a single-centre cohort study”.
Rheumatology 56, pp. 1552–1559.

Jenkins, DJ, BA Boucher, FD Ashbury, M Sloan, PE Brown, A El-Sohemy, AJ Hanley, W Willett, M Paquette, RJ de Souza, C Ireland, N Kwan, A Jenkins, SC Pichika, and N Kreiger. (2017).
“Effect of current dietary recommendations on weight loss and cardiovascular risk factors”.
Journal of the American College of Cardiology 69.9, pp. 1103–1112.

Rainham, D, PE Brown, and T Sampalli. (2017).
“Spatial variation in risk for physician diagnosed environmental sensitivity”.
Spatial and Spatio-temporal Epidemiology 23.

Tian, S, E Silverman, E Pullenayegum, PE Brown, J Beyene, and B Feldman. (2017).
“Comparative effectiveness of mycophenolate mofetil for the treatment of childhood-onset proliferative lupus nephritis”.
Arthritis Care and Research 69.

Aimone, AM, PE Brown, SH Zlotkin, DC Cole, and S Owusu-Agyei. (2016).
“Geo-spatial factors associated with infection risk among young children in rural Ghana a secondary spatial analysis”.
Malaria Journal 15.1, pp. 1–16.

Blumberger, DM, JJ Maller, L Thomson, BH Mulsant, TK Rajji, M Maher, PE Brown, J Downar, F Vila-Rodriguez, PB Fitzgerald, and ZJ Daskalakis. (2016).
“Unilateral and Bilateral MRI-Targeted Repetitive Transcranial Magnetic Stimulation for Treatment Resistant Depression A Randomized-Controlled Study”.
Journal of Psychiatry and Neuroscience 41.

Brown, PE, H Jiang, S Ezzat, and AM Sawka. (2016).
“A detailed spatial analysis on contrasting cancer incidence patterns in thyroid and lung cancer in Toronto women”.
BMC Public Health 16.1, p. 950.

Jiang, H, SD Walter, PE Brown, and AM Chiarelli. (2016).
“Estimation of Screening Sensitivity and Sojourn Time from an Organized Screening Program”.
Cancer Epidemiology 44, pp. 178–185.

Saint-Jacques, N, JSW Lee, PE Brown, J Stafford, L Parker, and TJB Dummer. (2016).
“Small-area spatio-temporal analyses of bladder and kidney cancer risk in Nova Scotia, Canada”.
BMC Public Health 16.175.

Wayne, N, N Cercone, J Li, A Zohar, J Katz, PE Brown, and P Ritvo. (2016).
“Data Mining of a Remote Behavioral Tracking System for Type 2 Diabetes Patients A Prospective Cohort Study”.
JMIR Diabetes 1.1.

Tian, SY, BM Feldman, J Beyene, PE Brown, EM Uleryk, and ED Silverman. (2015).
“Immunosuppressive Therapies for the Maintenance Treatment of Proliferative Lupus Nephritis: A Systematic Review and Network Metaanalysis”.
Journal of Rheumatology 42.8, pp. 1392–1400.

Fortune, MK, CA Mustard, and PE Brown. (2014).
“The use of Bayesian inference to inform the surveillance of temperature-related occupational morbidity in Ontario, Canada, 2004-2010”.
Environmental Research 132, pp. 449–456.

Rashid, S, A Sniderman, M Melone, PE Brown, JD Otvos, A Mente, K Schulze, MJ McQueen, SS Anand, and S Yusuf. (2014).
“Elevated cholesteryl ester transfer protein (CETP) activity, a major determinant of the atherogenic dyslipidemia, and atherosclerotic cardiovascular disease in South Asians”.
European Journal of Preventive Cardiology.

Rashid, S, H Tavori, PE Brown, MF Linton, J He, I Giunzioni, and S Fazio. (2014).
“PCSK9 Promotes Intestinal Overproduction of Triglyceride-Rich Apolipoprotein B Lipoproteins Through Both Low-Density Lipoprotein Receptor-Dependent and -Independent Mechanisms”.
Circulation 130.5, pp. 431–441.

Saint-Jacques, N, L Parker, PE Brown, and TJB Dummer. (2014).
“Arsenic in drinking water and urinary tract cancers: A systematic review of 30 years of epidemiological evidence”.
Environmental Health 13.

Sawka, AM, PE Brown, and S Ezzat. (2014).
“Temporal Trends in Thyroid Cancer Incidence in California–Letter”.
Cancer Epidemiology Biomarkers and Prevention 23.11, pp. 2609–2609.

Chiarelli, AM, SA Edwards, MV Prummel, D Muradali, V Majpruz, SJ Done, PE Brown, RS Shumak, and MJ Yaffe. (2013).
“Digital compared with screen-film mammography: performance measures in concurrent cohorts within an organized breast screening program”.
Radiology 268, pp. 684–693.

al-Maini, M, T Jeyalingam, PE Brown, JJY Lee, Y Li, J Su, DD Gladman, and PR Fortin. (2013).
“A hot spot for Lupus but not for psoriatic arthritis identified by spatial analysis suggests an interaction between race and place of residence”.
Arthritis and Rheumatism 65.

Wanigaratne, S, E Holowaty, H Jiang, TA Norwood, MA Pietrusiak, and PE Brown. (2013).
“Estimating cancer risk in relation to tritium exposure from routine operation of a nuclear-generating station in Pickering, Ontario”.
Chronic Diseases and Injuries in Canada 33.

Bagchi, R, PA Henrys, PE Brown, DFRP Burslem, P Diggle, C Gunatilleke, IAUN Gunatilleke, SP Hubbell, AR Kassim, S Noor, RL Valencia, and R Law. (2011).
“Spatial patterns reveal negative density dependence and habitat associations in tropical trees”.
Ecology 92, pp. 1723–172.

Perez, D, P Ritvo, PE Brown, and C Ardern. (2011).
“Perceived walkability, social support, age, native language & vehicle access as correlates of physical activity a cross-sectional study of low-SES, ethnic minority women.”
Journal of Physical Activity & Health 8, pp. 1098–1107.

Sullivan, AB, DC Gesink, PE Brown, L Zhou, JS Kaufman, M Fitch, ML Serre, and WC Miller. (2011).
“Are Neighborhood Sociocultural Factors Influencing the Spatial Pattern of Gonorrhea in North Carolina?”
Annals of Epidemiology 21.4, pp. 245–252.

Chiarelli, AM, V Majpruz, PE Brown, M Theriault, S Edwards, R Shumak, and V Mai. (2010).
“Influence of nurses on compliance with breast screening recommendations in an organized breast screening program”.
Cancer Epidemiology Biomarkers & Prevention 19, pp. 697–706.

Chiarelli, AM, V Majpruz, PE Brown, M Theriault, R Shumak, and V Mai. (2009).
“The contribution of clinical breast examination to the accuracy of breast screening.”
Journal of the National Cancer Institute 101, pp. 1236–1243.

Cole, DC, M Koehoorn, S Ibrahim, C Hertzman, A Ostry, F Xu, and PE Brown. (2009).
“Regions, hospitals and health outcomes over time: A multi-level analysis of repeat prevalence among a cohort of health-care workers”.
Health & Place 15, pp. 1046–57.

Look Hong, NJ, FC Wright, AR Gagliardi, PE Brown, and MJ Dobrow. (2009).
“Multidisciplinary cancer conferences: Exploring the attitudes of cancer care providers and administrators”.
Journal of Interprofessional Care 23, pp. 599–610.

Orchard, MC, MJ Dobrow, L Paszat, H Jiang, and PE Brown. (2009).
“Access to Electronic Health Records by care setting and provider type: Perceptions of cancer care providers in Ontario, Canada”.
BMC Medical Informatics and Decision Making 9.

Ritvo, P, R Myers, E Del Giudice, L Pazsat, M Cotterchio, R Howlett, V Mai, PE Brown, T Sullivan, and L Rabeneck. (2009).
“Fecal occult blood testing: People in Ontario are unaware of it and not ready for it”.
Canadian Family Physician 55, 176–7, e1–4.

Robinson, SE, PE Brown, EJ Wright, CA Hart, PJ Diggle, and NP French. (2008).
“Quantifying within and between-animal variation and uncertainty associated with counts of Escherichia coli O157 occurring in naturally infected cattle faeces”.
Interface 6, pp. 169–177.

Russo, SE, PE Brown, S Tan, and SJ Davies. (2008).
“Interspecific demographic trade-offs and edaphic niche specialization of tree species along resource gradients”.
Journal of Ecology 96, pp. 192–203.

Pleydell, EJ, PE Brown, MJ Woodward, RH Davies, and NP French. (2007).
“Sources of variation in the Ampicillin-resistant Escherichia coli concentration in the feces of organic broiler chickens”.
Applied and Environmental Microbiology 73, pp. 203–210.

Romanowicz, R, PC Young, PE Brown, and PJ Diggle. (2006).
“A recursive estimation approach to the spatio-temporal analysis and modelling of air quality data”.
Environmental Modelling and Software 6, pp. 759–769.

French, N, M Barrigas, PE Brown, PJ Ribeiro, N Williams, H Leatherbarrow, R Birtles, E Bolton, P Fearnhead, and A Fox. (2005).
“Spatial epidemiology and natural population structure of Campylobacter jejuni colonising a farmland ecosystem.”
Environmental Microbiology 7, pp. 1116–1126.

Parkin, TDH, PE Brown, NP French, and KL Morgan. (2005).
“Cooking the books or simply getting the best out of the data? Assessing the nature of the relationship between variables”.
Equine Veterinary Journal 37.3, pp. 189–191.

Swai, ES, NP French, ED Karimuribo, JL Fitzpatrick, MJ Bryant, PE Brown, and NH Ogden. (2005).
“Spatial and management factors associates with exposure of smallholder dairy cattle in Tanzania to tick-borne pathogens”.
International Journal for Parasitology 35, pp. 513–525.

Brown, PE, OF Christensen, HE Clough, PJ Diggle, CA Hart, S Hazel, R Kemp, AJ Leatherbarrow, A Moore, J Sutherst, J Turner, NJ Williams, EJ Wright, and NP French. (2004).
“Frequency and spatial distribution of environmental Campylobacter spp.
Applied and Environmental Microbiology 70.11, pp. 6501–6511.

Robinson, SE, PE Brown, EJ Wright, M Bennett, A Hart, and NP French. (2004).
“Heterogeneous distributions of Escherichia coli O157 within naturally infected bovine faecal pats”.
FEMS Microbiology Letters 244, pp. 291–296.

4.3 Unpublished

Brown, PE and PA Henrys. “Longitudinal Spatial Point Processes”. 2013.

Brown, PE and H Jiang. “Intraclass Correlation and the Design Effect for Binary Random Effects Models”. Unpublished. 2010.

Clough, H, PE Brown, J Sanderson, and A Cook. “Spatial and temporal variation in Salmonella levels on UK pig farms: A case study in modelling large routine surveillance datasets”. Unpublished. 2010.

Henrys, PA and PE Brown. “Spectral analysis of inhomogeneous clustered spatial point processes”. Unpublished. 2010.